Following the occupation of Czechoslovakia by Nazi Germany in March 1939, and the declaration of a Slovak republic on March 14, Hitler announced on March 15 the establishment of the Protectorate of Bohemia and Moravia. Between 1939 and 1941 the Nazi authorities in the Protectorate carried out various anti-Jewish measures, which included the harassment of Jews and of Jewish institutions and the confiscation of property.
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On October 10, 1941, the newly appointed Reichsprotektor, Reinhard Heydrich, summoned several SS officers, among them Adolf Eichmann, to a meeting in Prague (Praha). Heydrich, who was also chief of the Reich Main Security Office (Reichssicherheitshauptamt, RSHA), revealed a plan to deport 5,000 Jews from the Protectorate to Eastern Europe and in addition to expel the remaining Jews of the Protectorate to an assembly camp in Bohemia. Theresienstadt, a garrison town built in the 18th century, located about 6 kilometers north of Prague, was chosen to serve as the place for concentrating the Jews of Bohemia and Moravia.
Mass deportations of Jews from Prague and soon afterwards from other large cities began in late November 1941.

Transport G left Brno for the Theresienstadt Ghetto on December 2, 1941. According to existing deportation lists it consisted of 1,000 Jews, residents of Brno. It was the first of ten transports from Brno to the Ghetto established in the Protectorate. The deportees were first brought to a collection point at a school building on Merhautova St. 37 in Brno.

Prior to the train’s departure, several staff members of the Prague Jewish community Transports Department arrived in Brno to carry out administrative measures according to the orders they received from the Central Office for Jewish Immigration. They prepared a list of deportees, registered Jewish property, issued notices regarding the date of deportation and assisted in packing and carrying luggage.

From the assembly site, the deportees were transferred to the train station and put on a train. Upon its arrival in Bohusovice, the Jews had to disembark and were forced to march the remaining 3 km to Theresienstadt.

According to historian Anita Frankova, a third of the deportees had already been sent to Riga on Transport O a month later, on January 9, 1942.
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